College football odds, picks, predictions for Week 3, 2023: Proven model backs Tennessee, Purdue

joe milton cbs

No. 10 Alabama cannot afford another poor performance during the Week 3 college football schedule after losing to Texas at home in Week 2. The Crimson Tide are expected to take care of business as 32-point favorites at South Florida in the Week 3 college football odds. They have already covered as heavy favorites once this season, cruising to a 56-7 win over Middle Tennessee as 39.5-point favorites in Week 1. Should you back Alabama with your Week 3 college football bets?

No. 4 Texas is a 28-point home favorite against Wyoming in the Week 3 college football spreads, as it looks to avoid a letdown game. Wyoming has already sprung one big upset this season, taking down Texas Tech as a 13.5-point underdog in its season opener. Before locking in any college football picks on those games or others, be sure to see the latest college football predictions from SportsLine’s proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of nearly $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest college football odds for Week 3 and locked in picks for every FBS matchup. Head here to see every pick.

Top college football predictions for Week 3

One of the college football picks the model is recommending for Saturday: No. 11 Tennessee (-7) wins by double digits at Florida in a 7 p.m. ET kickoff at Ben Hill Griffin Stadium. The Vols have been one of the best teams in the country since the beginning of last season, winning 13 of their last 15 games. They have not won in Gainesville since 2003, but the Gators have only won and covered the spread once in their last five games since the end of last year.

Florida struggled against Utah in its season opener, scoring just 11 points and going 1 of 13 on third down. Tennessee will be an equally difficult opponent, as the Vols cruised to a 49-13 win over Virginia in their first game. They have covered the spread in 11 of their last 15 games, and the model has them covering almost 60% of the time in Week 3. 

Another prediction: Purdue (+2.5) beats Syracuse outright on Saturday at 7:30 p.m. ET. Syracuse got past Purdue by a field goal at home last season, but the Orange have struggled on the road, winning just five of their last 20 road games. They have also won just three of their last 17 games against Big Ten opponents.

Purdue could easily be 2-0 right now, as it blew a double-digit lead in the second half of its season opener against Fresno State before taking down Virginia Tech as a road underdog last week. The Boilermakers are led by junior quarterback Hudson Card, who has thrown for 502 yards and two touchdowns this season. He is facing a Syracuse defense that has not been challenged so far this season, beating Colgate and Western Michigan at home. This will be a major step up in competition for the Orange, which is one reason why the Boilermakers are covering the spread in almost 70% of simulations. See which other teams the model likes here.

How to make college football picks for Week 3

The model has also made the call on who wins and covers in every other FBS matchup in Week 3, and it’s calling for several other underdogs to win outright. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence, and which underdogs win outright? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned nearly $2,500 in profit since its inception, and find out.

College football odds for Week 3 top games 

See full Week 3 college football picks, odds, predictions here

Thursday, Sept. 14

Navy at Memphis (-14.5, 47.5)

Friday, Sept. 15

Virginia at Maryland (-14, 50.5)

Army at UTSA (-11, 46)

Utah State at Air Force (-9, 47)

Saturday, Sept. 16

Florida State at Boston College (+27.5, 55)

Louisville at Indiana (+10, 54)

Penn State at Illinois (+14, 48.5)

LSU at Mississippi State (+10, 53)

Kansas State at Missouri (+5.5, 46)

South Carolina at Georgia (-27, 55)

Minnesota at North Carolina (-7.5, 49)

Washington at Michigan State (+16, 58)

Tennessee at Florida (+7, 57.5)

BYU at Arkansas (-10, 52)

TCU at Houston (+7.5, 62)

Colorado State at Colorado (-22.5, 59)

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